The carbohydrate moiety of many vertebrate glycoproteins bears terminal residues of sialic acid. If such residues are removed, eg. by treatment with a neuraminidase, the resulting proteins are known as asialoglycoproteins. In the case of certain plasma proteins, the asialo-derivatives are specifically bound by a receptor on the surface of liver parenchymal cells (the scavenger receptor).

Dictionary of molecular biology. 2004.

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  • Asialoglycoprotein receptor — protein Name=asialoglycoprotein receptor 1 caption= width= HGNCid=742 Symbol=ASGR1 AltSymbols= EntrezGene=432 OMIM=108360 RefSeq=NM 001671 UniProt=P07306 PDB= ECnumber= Chromosome=17 Arm=p Band=13 LocusSupplementaryData= p11protein… …   Wikipedia

  • Asialoglycoprotein — If terminal sialic acid residues are removed from glycoproteins, the resulting proteins are known as asialoglycoproteins. These are transmembrane proteins where the amino terminal is cytosolic and the carboxyl terminal is exoplasmic.These… …   Wikipedia

  • asialoglycoprotein — noun Any glycoprotein from which the sialic acid residues have been removed …   Wiktionary

  • asialoglycoprotein — A glycoprotein without a sialic acid moiety; such proteins are recognized by a. receptors and are targeted for degradation …   Medical dictionary

  • ASGP — asialoglycoprotein …   Medical dictionary

  • ASGP — • asialoglycoprotein …   Dictionary of medical acronyms & abbreviations

  • ASGR — asialoglycoprotein receptor …   Medical dictionary

  • ASGR — • asialoglycoprotein receptor …   Dictionary of medical acronyms & abbreviations

  • N-Acetylglucosamine receptor — heterogeneous nuclear ribonucleoprotein M Identifiers Symbol HNRPM Alt. symbols NAGR1 Entrez 4670 …   Wikipedia

  • Neurocan — Identifiers Symbols NCAN; CSPG3; FLJ44681 External IDs OMIM:  …   Wikipedia

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